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APCS 抗体 (AA 143-223)

This anti-APCS antibody is a 小鼠 单克隆 antibody detecting APCS in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939659
发货至: 中国

Quick Overview for APCS 抗体 (AA 143-223) (ABIN6939659)

抗原

See all APCS 抗体
APCS (Amyloid P Component, Serum (APCS))

适用

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宿主

  • 69
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  • 1
小鼠

克隆类型

  • 72
  • 35
单克隆

标记

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  • 1
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This APCS antibody is un-conjugated

应用范围

  • 72
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  • 1
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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

APCS-3240
  • 抗原表位

    • 14
    • 12
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 143-223

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment of human APCS protein (around aa 143-223) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Human endometrial carcinoma tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    APCS (Amyloid P Component, Serum (APCS))

    别名

    APCS

    背景

    Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.

    分子量

    200kDa (oligomeric), 26kDa (non-covalently bound subunit), 30kDa (glycosylated SAP subunit)

    基因ID

    325

    UniProt

    P02743
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