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AMPD3 抗体

This anti-AMPD3 antibody is a 小鼠 单克隆 antibody detecting AMPD3 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939530
发货至: 中国

Quick Overview for AMPD3 抗体 (ABIN6939530)

抗原

See all AMPD3 抗体
AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This AMPD3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

AMPD3-901
  • 特异性

    It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full-length human AMDP3 protein

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: RBC. Fetal liver, Spleen or Placenta.

    Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

    别名

    AMPD3

    分子量

    ~90kDa

    基因ID

    272

    UniProt

    Q01432
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