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ALPL 抗体

This anti-ALPL antibody is a 小鼠 单克隆 antibody detecting ALPL in IHC 和 StM. Suitable for 人 和 Cow.
产品编号 ABIN6939448
发货至: 中国

Quick Overview for ALPL 抗体 (ABIN6939448)

抗原

See all ALPL 抗体
ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

适用

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人, Cow

宿主

  • 93
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小鼠

克隆类型

  • 92
  • 29
单克隆

标记

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This ALPL antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

ALPL-597
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human ALPL protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Intestine.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

    别名

    ALPL

    背景

    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.

    分子量

    55kDa

    基因ID

    249

    UniProt

    P05186
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