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Frataxin 抗体 (AA 57-210)

This anti-Frataxin antibody is a 小鼠 单克隆 antibody detecting Frataxin in WB, IHC 和 StM. Suitable for 人.
产品编号 ABIN6939442
发货至: 中国

Quick Overview for Frataxin 抗体 (AA 57-210) (ABIN6939442)

抗原

See all Frataxin (FXN) 抗体
Frataxin (FXN)

适用

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宿主

  • 57
  • 17
小鼠

克隆类型

  • 59
  • 15
单克隆

标记

  • 49
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This Frataxin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

FXN-2124
  • 抗原表位

    • 9
    • 7
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    AA 57-210

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: HepG2, Panc-2, HL-60 or HEK293 cells. Pancreas and Liver.

    Known Application: Western Blot (0.5-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Frataxin (FXN)

    别名

    FXN

    背景

    Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

    分子量

    14kDa

    基因ID

    2395

    UniProt

    Q16595

    途径

    Transition Metal Ion Homeostasis, Regulation of Cell Size
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