AKR1B1 抗体
Quick Overview for AKR1B1 抗体 (ABIN6939403)
抗原
See all AKR1B1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            纯化方法
- Purified by Protein A/G
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                                            免疫原
- Recombinant human full-length AKR1B1 protein
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                                            亚型
- IgG1 kappa
 
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                                            应用备注
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                        Positive Control: 293T, HEK293, A431, HeLa, HepG2, MOLT4, Jurkat and Raji whole cell lysates, Human Kidney, Human colon carcinoma tissue. Known Application: Western Blot (1-2 μg/mL),Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined. 
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                                            限制
- 仅限研究用
 
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                                            浓度
- 200 μg/mL
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                                            缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-80 °C
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                                            储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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                                            有效期
- 24 months
 
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    - AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
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                                            别名
- AKR1B1
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                                            背景
- AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
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                                            分子量
- 37kDa
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                                            基因ID
- 231
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                                            UniProt
- P15121
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                                            途径
- Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
 抗原
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