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DBN1 抗体 (AA 150-281)

This 小鼠 单克隆 anti-DBN1 antibody (Clone DBN1-2879) specifically detects DBN1 in IHC 和 StM. The antibody is reactive with 人 samples.
产品编号 ABIN6939227
发货至: 中国
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Quick Overview for DBN1 抗体 (AA 150-281) (ABIN6939227)

抗原

See all DBN1 抗体
DBN1 (Drebrin 1 (DBN1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DBN1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

DBN1-2879
  • 抗原表位

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    AA 150-281

    免疫原

    Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    DBN1 (Drebrin 1 (DBN1))

    别名

    DBN1

    背景

    Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

    分子量

    120kDa

    基因ID

    1627

    UniProt

    Q16643

    途径

    Maintenance of Protein Location
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