DBN1 抗体 (AA 150-281)
Quick Overview for DBN1 抗体 (AA 150-281) (ABIN6939227)
抗原
See all DBN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-281
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免疫原
- Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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应用备注
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Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- DBN1 (Drebrin 1 (DBN1))
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别名
- DBN1
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背景
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
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分子量
- 120kDa
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基因ID
- 1627
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UniProt
- Q16643
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途径
- Maintenance of Protein Location
抗原
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