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Cathepsin K 抗体 (AA 163-274)

This anti-Cathepsin K antibody is a 小鼠 单克隆 antibody detecting Cathepsin K in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939219
发货至: 中国

Quick Overview for Cathepsin K 抗体 (AA 163-274) (ABIN6939219)

抗原

See all Cathepsin K (CTSK) 抗体
Cathepsin K (CTSK)

适用

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宿主

  • 84
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小鼠

克隆类型

  • 87
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单克隆

标记

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This Cathepsin K antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

CTSK-2791
  • 抗原表位

    • 33
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    AA 163-274

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Human liver or breast tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Cathepsin K (CTSK)

    别名

    CTSK

    背景

    The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

    分子量

    39kDa

    基因ID

    1513

    UniProt

    P43235

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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