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CPA1 抗体

This anti-CPA1 antibody is a 小鼠 单克隆 antibody detecting CPA1 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939171
发货至: 中国

Quick Overview for CPA1 抗体 (ABIN6939171)

抗原

See all CPA1 抗体
CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))

适用

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宿主

  • 55
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小鼠

克隆类型

  • 53
  • 44
单克隆

标记

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This CPA1 antibody is un-conjugated

应用范围

  • 93
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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

CPA1-2711
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full-length human CPA1 protein

    亚型

    IgG kappa
  • 应用备注

    Positive Control: Pancreas.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))

    别名

    CPA1

    背景

    Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

    分子量

    47kDa

    基因ID

    1357

    UniProt

    P15085
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