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Recombinant Chromogranin A 抗体

This anti-Chromogranin A antibody is a 兔 单克隆 antibody detecting Chromogranin A in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939136
发货至: 中国

Quick Overview for Recombinant Chromogranin A 抗体 (ABIN6939136)

抗原

See all Chromogranin A (CHGA) 抗体
Chromogranin A (CHGA)

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This Chromogranin A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

CHGA-1731R
  • 特异性

    Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

    无交叉反应

    大鼠

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human full-length chromogranin A(CHGA) protein

    亚型

    IgG
  • 应用备注

    Positive Control: PC12 cells. Adrenal gland, bowel, parathyroid, pancreas or pheochromocytoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Chromogranin A (CHGA)

    别名

    CHGA

    分子量

    68-75kDa

    基因ID

    1113

    UniProt

    P10645

    途径

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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