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CGB 抗体

This anti-CGB antibody is a 小鼠 单克隆 antibody detecting CGB in IHC (fro). Suitable for 人.
产品编号 ABIN6939105
发货至: 中国

Quick Overview for CGB 抗体 (ABIN6939105)

抗原

See all CGB 抗体
CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CGB antibody is un-conjugated

应用范围

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Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

HCGb-211
  • 特异性

    This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

    交叉反应 (详细)

    Human,

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Purified human HCG-beta

    亚型

    IgG1
  • 应用备注

    Positive Control: Placenta.

    Known Application: Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

    有效期

    24 months
  • 抗原

    CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

    别名

    CGB

    背景

    CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB,HCG-beta (Pregnancy & Choriocarcinoma Marker)
    Cellular localisation: Cytoplasmic, secreted

    分子量

    22kDa

    基因ID

    1082, 172944

    UniProt

    P01233
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