Podoplanin 抗体 (AA 24-126)
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北京 101111
Quick Overview for Podoplanin 抗体 (AA 24-126) (ABIN6939085)
抗原
See all Podoplanin (PDPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 24-126
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特异性
- It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
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交叉反应 （详细）
- Human,
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human Podoplanin (PDPN) protein fragment (around aa 24-126) (exact sequence is proprietary)
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亚型
- IgG1
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anti-Podoplanin (PDPN) (AA 91-166) antibody
PDPN 适用: 小鼠, 大鼠 WB, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) (AA 23-143) antibodyPDPN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) antibodyPDPN 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1445 unconjugated Recombinant Antibody
anti-Podoplanin (PDPN) antibodyPDPN 适用: 小鼠 WB, FACS, IP, IHC (p) 宿主: 大鼠 Monoclonal 8F11 unconjugated
anti-Podoplanin (PDPN) antibodyPDPN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) (AA 1-206) antibodyPDPN 适用: 人 ELISA, FACS, IF, ICC 宿主: 小鼠 Monoclonal 5E2 unconjugated
anti-Podoplanin (PDPN) (AA 99-207) antibodyPDPN 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT56F7 unconjugated
anti-Podoplanin (PDPN) (N-Term) antibodyPDPN 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) antibodyKD Validated PDPN 适用: 人 WB 宿主: 兔 Monoclonal 25GB7870 unconjugated Recombinant Antibody
anti-Podoplanin (PDPN) antibodyPDPN 适用: 小鼠 WB, IP, IHC (fro) 宿主: Golden Syrian Hamster Monoclonal 811 unconjugated
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应用备注
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Positive Control: HeLa cells. Cervical or Lung Carcinoma.
Known Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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: "Vascularized in vitro bone model as 3D quadruple culture with primary human osteoblasts, osteocytes, osteoclasts and endothelial cells." in: Materials today. Bio, Vol. 34, pp. 102154, (2025) (PubMed).
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: "Vascularized in vitro bone model as 3D quadruple culture with primary human osteoblasts, osteocytes, osteoclasts and endothelial cells." in: Materials today. Bio, Vol. 34, pp. 102154, (2025) (PubMed).
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- Podoplanin (PDPN)
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别名
- PDPN
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背景
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Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8, PA2.26, Pdpn, Podoplanin, PSEC0003, PSEC0025, T1-alpha, T1A, TI1A, TIA2,Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)
Cellular localisation: Cell Surface and Cytoplasmic -
分子量
- 38-43kDa
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基因ID
- 10630, 468675
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UniProt
- Q86YL7
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途径
- Dicarboxylic Acid Transport
抗原
-
