TUBB3 抗体 (AA 437-450)
Quick Overview for TUBB3 抗体 (AA 437-450) (ABIN6939054)
抗原
See all TUBB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 437-450
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特异性
- This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3.In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.
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交叉反应 (详细)
- Human. Others not known.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- A synthetic peptide (aa 437-450) of human Tubulin beta 3 protein (TUBB3), coupled to KLH.
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亚型
- IgG1
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应用备注
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Positive Control: U87, A375, Raji, HEP2 cells. Brain and Testis
Known Application: Western Blotting (1-2 μg/mL),Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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- TUBB3 (Tubulin, beta 3 (TUBB3))
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别名
- TUBB3
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背景
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Beta 3 tubulin, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, TUBB3, TUBB4, Tubulin beta-3, Tubulin beta-4, Tubulin beta-III,Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker)
Cellular localisation: Cytoplasmic -
分子量
- 55kDa
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基因ID
- 10381, 511743
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UniProt
- Q13509
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途径
- Microtubule Dynamics, M Phase
抗原
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