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LI Cadherin 抗体 (AA 242-418)

This anti-LI Cadherin antibody (ABIN6939028) is a Mouse Monoclonal antibody detecting LI Cadherin in WB, IHC (f). Suitable for Human.
产品编号 ABIN6939028
发货至: 中国

Quick Overview for LI Cadherin 抗体 (AA 242-418) (ABIN6939028)

抗原

See all LI Cadherin 抗体
LI Cadherin

适用

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  • 10
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宿主

  • 36
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  • 5
小鼠

克隆类型

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  • 3
单克隆

标记

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This LI Cadherin antibody is un-conjugated

应用范围

  • 32
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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

CDH17-2617
  • 抗原表位

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    AA 242-418

    特异性

    It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

    交叉反应 (详细)

    Human,

    纯化方法

    200ug/ml of Ab Purified from rabbit anti-serum by Protein A.

    免疫原

    Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)

    亚型

    IgG2b
  • 应用备注

    Positive Control: HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

    有效期

    24 months
  • 抗原

    LI Cadherin

    别名

    CDH17

    背景

    BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin,Cadherin 17 / LI Cadherin (Liver-Intestine Marker)
    Cellular localisation: Cell Surface and Cytoplasmic

    分子量

    120kDa

    基因ID

    1015, 591853

    UniProt

    Q12864
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