P-Cadherin 抗体
Quick Overview for P-Cadherin 抗体 (ABIN6939015)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.
-
交叉反应 (详细)
- Human,
-
纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant human P-cadherin fusion protein
-
亚型
- IgG1
-
-
-
-
应用备注
-
Positive Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
-
有效期
- 24 months
-
-
- P-Cadherin (CDH3)
-
别名
- CDH3
-
背景
-
Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin,P-Cadherin (CDH3)
Cellular localisation: Cell surface -
分子量
- 116kDa
-
基因ID
- 1001, 191842
-
UniProt
- P22223
抗原
-