Uroplakin 3A 抗体 (AA 260-279)
Quick Overview for Uroplakin 3A 抗体 (AA 260-279) (ABIN6938735)
抗原
See all Uroplakin 3A (UPK3A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-279
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特异性
- Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
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亚型
- IgG
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HEK293 cells. Bladder carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Uroplakin 3A (UPK3A)
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别名
- UPK3A
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背景
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UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A,Uroplakin 3A (Bladder Carcinoma Marker)
Cellular localisation: Cell surface -
分子量
- 30kDa
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基因ID
- 7380, 632787
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UniProt
- O75631
抗原
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