TSH receptor 抗体
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- 抗原 See all TSH receptor (TSHR) 抗体
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TSH receptor antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave's disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human TSHR, B-Chain protein
- 克隆位点
- SPM222
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TSHR Primary Antibody
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anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 21-253) antibody
TSHR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 501-600) antibodyTSHR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 201-300) antibodyTSHR 适用: 人, 小鼠 ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 648-740) antibodyTSHR 适用: 人, 小鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 28-245) antibodyTSHR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (C-Term) antibodyTSHR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (N-Term) antibodyTSHR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) antibodyTSHR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TSHRB-1405 unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) antibodyTSHR 适用: 人 ELISA, IHC, StM, Coat 宿主: 小鼠 Monoclonal TSHRA-1402 unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (Internal Region) antibodyTSHR 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 8.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: 293T cells. Thyroid gland.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
- 别名
- TSHR (TSHR 产品)
- 背景
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CHNG1, hTSHRI, LGR3, Thyroid-stimulating hormone receptor, Thyrotropin receptor, Thyrotropin receptor I, TSHR,TSH-Receptor, B-Chain (Thyroid Marker)
Cellular localisation: Cell Surface & Cytoplasmic - 分子量
- 42kDa
- 基因ID
- 7253, 160411
- UniProt
- P16473
- 途径
- Thyroid Hormone Synthesis
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