TPSAB1 抗体 (AA 115-233)
Quick Overview for TPSAB1 抗体 (AA 115-233) (ABIN6938670)
抗原
See all TPSAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 115-233
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特异性
- Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human Tryptase protein fragment (around aa 115-233) (Exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibody
TPSAB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibodyTPSAB1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 161-262) antibodyTPSAB1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C17 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 151-275) antibodyTPSAB1 适用: 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 1-275) antibodyTPSAB1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A10-B5 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 19-210) antibodyTPSAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 115-233) antibodyTPSAB1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TPSAB1-1961 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 149-273) antibodyTPSAB1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 151-275) antibodyTPSAB1 适用: 犬 WB 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Tryptase alpha/beta 1 (TPSAB1) (AA 1-275) antibodyTPSAB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Skin or Tonsil.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
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别名
- TPSAB1
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背景
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Lung Tryptase, Mast cell alpha II Tryptase, Mast cell beta I Tryptase, Mast cell protease 7, Mast cell protease II, MCP7, Pituitary Tryptase, Skin Tryptase, TPS1, TPSAB1, TPSB1, Tryptase 1, Tryptase alpha 1, Tryptase skin,Tryptase (Mast Cell Marker)
Cellular localisation: Secreted and Cytoplasmic -
分子量
- 31-36kDa
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基因ID
- 7177, 405479
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UniProt
- Q15661
抗原
-
