TIMP3 抗体 (AA 175-211)
Quick Overview for TIMP3 抗体 (AA 175-211) (ABIN6938581)
抗原
See all TIMP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 175-211
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特异性
- TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.
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交叉反应 （详细）
- Human. Mouse. Rat. Horse. Cow. Dog.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in Mouse and rat.
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亚型
- IgG
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anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (Internal Region) antibody
TIMP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 151-211) antibodyTIMP3 适用: 人, 大鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 26-211) antibodyTIMP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 113-139) antibodyTIMP3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21049 unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 170-188) antibodyTIMP3 适用: 人, Cow, 犬, 马, Pig, 绵羊, 猴 WB, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 27-209) antibodyTIMP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 119-148), (Middle Region) antibodyTIMP3 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 176-210), (C-Term) antibodyTIMP3 适用: 人 WB 宿主: 兔 Polyclonal RB47669 unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 1-184) antibodyTIMP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 3 (TIMP3) (AA 30-208) antibodyTIMP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Placenta or breast carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
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别名
- TIMP3
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背景
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HSMRK222, K222TA2, Protein MIG-5, SFD, Sorsby fundus dystrophy pseudo-inflammatory, TIMP metallopeptidase inhibitor 3, Tissue Inhibitor of Metalloproteinase 3,TIMP-3 (Tissue Inhibitor of Metalloproteinase-3)
Cellular localisation: Cytoplasmic -
分子量
- 30kDa
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基因ID
- 7078, 644633, 714168
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UniProt
- P35625
抗原
-
