Recombinant TIMP1 抗体
Quick Overview for Recombinant TIMP1 抗体 (ABIN6938574)
抗原
See all TIMP1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length TIMP1 protein
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亚型
- IgG
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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 103-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 157-188), (C-Term) antibodyTIMP1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB14602 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 41-70), (N-Term) antibodyTIMP1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB15494 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-207) antibodyTIMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibodyTIMP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibodyTIMP1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 8B4E9 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) antibodyTIMP1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibodyTIMP1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 131-207) antibodyTIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-217) antibodyTIMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: 293 cell extract or rat brain lysate. Human colon carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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别名
- TIMP1
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背景
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Clgi, Collagenase inhibitor, Collagenase inhibitor, Human, EPA, EPO, Erythroid Potentiating Activity, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, FLJ90373, HCI, Human Collagenase Inhibitor, Metalloproteinase inhibitor 1, Metalloproteinase inhibitor 1 precursor, TIMP 1, TIMP, TIMP metallopeptidase inhibitor 1, TIMP-1, TIMP1 protein, Tissue Inhibitor of Metalloproteinase 1, Tissue inhibitor of metalloproteinases 1,TIMP1 (Colorectal and Lymph Node Metastasis Marker)
Cellular localisation: Secreted. Cytoplasm. -
分子量
- 23kDa
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基因ID
- 7076, 522632
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UniProt
- P01033
抗原
-
