Recombinant Thrombomodulin 抗体 (AA 69-194)
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- 抗原 See all Thrombomodulin (THBD) 抗体
- Thrombomodulin (THBD)
- 抗体类型
- Recombinant Antibody
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抗原表位
- AA 69-194
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Thrombomodulin antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat), Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)
- 克隆位点
- RTHBD-1591
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product THBD Primary Antibody
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- 应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: THP1 cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Thrombomodulin (THBD)
- 别名
- THBD (THBD 产品)
- 别名
- AHUS6 antibody, BDCA3 antibody, CD141 antibody, THPH12 antibody, THRM antibody, TM antibody, AI385582 antibody, THBD antibody, HAST antibody, HAST3 antibody, M-PST antibody, ST1A3/ST1A4 antibody, ST1A5 antibody, STM antibody, TL-PST antibody, thrombomodulin antibody, sulfotransferase family 1A member 3 antibody, THBD antibody, Thbd antibody, SULT1A3 antibody
- 背景
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AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM),Thrombomodulin / CD141 (Endothelial Cell Marker)
Cellular localisation: Cell Surface & Cytoplasmic - 分子量
- ~100kDa
- 基因ID
- 7056, 2030
- UniProt
- P07204
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