Recombinant Thrombomodulin 抗体 (AA 69-194)
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Quick Overview for Recombinant Thrombomodulin 抗体 (AA 69-194) (ABIN6938551)
抗原
See all Thrombomodulin (THBD) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 69-194
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原理
- Recombinant Thrombomodulin / CD141 (Endothelial Cell Marker) Antibody
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特异性
- It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Thrombomodulin (THBD) (AA 17-515) antibody
THBD 适用: 人 WB, IHC, IP, FACS, ICC 宿主: 兔 Monoclonal BLR253L unconjugated Recombinant Antibody
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal THBD-1591 unconjugated
anti-Thrombomodulin (THBD) (AA 200-500) antibodyTHBD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 17-515) antibodyTHBD 适用: 人 WB, IHC, IP, FACS, ICC 宿主: 兔 Monoclonal BLR253L unconjugated Recombinant Antibody
anti-Thrombomodulin (THBD) (C-Term) antibodyTHBD 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal rTHBD-1591 unconjugated Recombinant Antibody
anti-Thrombomodulin (THBD) (AA 69-194) antibodyTHBD 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal THBD-1782 unconjugated
anti-Thrombomodulin (THBD) (AA 297-505) antibodyTHBD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C6C3 unconjugated
anti-Thrombomodulin (THBD) (C-Term) antibodyTHBD 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thrombomodulin (THBD) (AA 92-126) antibodyTHBD 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB56919 unconjugated
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应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: THP1 cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Thrombomodulin (THBD)
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别名
- THBD
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背景
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AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM)
Angiosarcoma, Bladder or Cervical Carcinoma., THP1 cells. Placenta
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分子量
- 100kDa
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基因ID
- 7056, 2030
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UniProt
- P07204
抗原
-
