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Transferrin Receptor 抗体

This anti-Transferrin Receptor antibody is a 小鼠 单克隆 antibody detecting Transferrin Receptor in FACS, ELISA, IF 和 Coat. Suitable for 人.
产品编号 ABIN6938535
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (ABIN6938535)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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小鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat)

克隆位点

66IG10
  • 特异性

    It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human thymocytes (T-cells)

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    TFRC

    背景

    Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR,CD71 / Transferrin Receptor (TFRC)
    Cellular localisation: Cell surface

    分子量

    85-95kDa (monomer), 190kDa (dimer)

    基因ID

    7037, 529618

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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