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Transferrin Receptor 抗体

This anti-Transferrin Receptor antibody is a 小鼠 单克隆 antibody detecting Transferrin Receptor in FACS, WB 和 IF. Suitable for 人.
产品编号 ABIN6938534
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (ABIN6938534)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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小鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

克隆位点

DF1513
  • 特异性

    It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    KG1 acute myeloid leukemia cell line

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    TFRC

    背景

    Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR,CD71 / Transferrin Receptor (TFRC)
    Cellular localisation: Cell surface

    分子量

    85-95kDa (monomer), 190kDa (dimer)

    基因ID

    7037, 529618

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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