TAL1 抗体
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- 抗原 See all TAL1 抗体
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TAL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Coating (Coat)
- 特异性
- Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human full-length TAL1 protein
- 克隆位点
- BTL73
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TAL1 Primary Antibody
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anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibody
TAL1 适用: 人, 犬, Cow, 豚鼠, 马, 兔, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 适用: 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 1-114) antibodyTAL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 154-188) antibodyTAL1 适用: 人 WB 宿主: 兔 Polyclonal RB50954 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 236-285) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: A549 xenograft.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
- 别名
- TAL1 (TAL1 产品)
- 别名
- SCL/tal-1 antibody, Scl antibody, bHLHa17 antibody, tal-1 antibody, SCL antibody, TCL5 antibody, scl antibody, tcl5 antibody, SCL-alpha antibody, SCL-beta antibody, scl/tal1 antibody, zgc:85605 antibody, T cell acute lymphocytic leukemia 1 antibody, TAL bHLH transcription factor 1, erythroid differentiation factor antibody, T-cell acute lymphocytic leukemia 1 S homeolog antibody, T-cell acute lymphocytic leukemia 1 antibody, Tal1 antibody, TAL1 antibody, tal1.S antibody, tal1 antibody
- 背景
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BHLHa17, Class A basic helix-loop-helix protein 17, OTTHUMP00000009563, OTTHUMP00000009564, SCL, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, Stem cell protein, T cell acute lymphocytic leukemia 1, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1 protein, T cell leukemia/lymphoma 5 protein, T-cell acute lymphocytic leukemia protein 1, T-cell leukemia/lymphoma protein 5, Tal 1 product, TAL 1 protein, TAL bHLH transcription factor 1 erythroid differentiation factor, TAL-1,Tal1
Cellular localisation: Nuclear. - 分子量
- 42kDa
- 基因ID
- 6886, 705618
- UniProt
- P17542
- 途径
- Stem Cell Maintenance
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