TAL1 抗体
Quick Overview for TAL1 抗体 (ABIN6938514)
抗原
See all TAL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length TAL1 protein
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亚型
- IgG1 kappa
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anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibody
TAL1 适用: 人, 犬, Cow, 豚鼠, 马, 兔, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 1-114) antibodyTAL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 154-188) antibodyTAL1 适用: 人 WB 宿主: 兔 Polyclonal RB50954 unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) antibodyTAL1 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (C-Term) antibodyTAL1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (AA 236-285) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Acute Lymphocytic Leukemia 1 (TAL1) (N-Term) antibodyTAL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: A549 xenograft.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
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别名
- TAL1
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背景
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BHLHa17, Class A basic helix-loop-helix protein 17, OTTHUMP00000009563, OTTHUMP00000009564, SCL, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, Stem cell protein, T cell acute lymphocytic leukemia 1, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1 protein, T cell leukemia/lymphoma 5 protein, T-cell acute lymphocytic leukemia protein 1, T-cell leukemia/lymphoma protein 5, Tal 1 product, TAL 1 protein, TAL bHLH transcription factor 1 erythroid differentiation factor, TAL-1,Tal1
Cellular localisation: Nuclear. -
分子量
- 42kDa
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基因ID
- 6886, 705618
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UniProt
- P17542
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途径
- Stem Cell Maintenance
抗原
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