Recombinant TAG-72 / CA72.4 抗体
Quick Overview for Recombinant TAG-72 / CA72.4 抗体 (ABIN6938510)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
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纯化方法
- Purified by Protein A/G
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免疫原
- Purified TAG-72 protein
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亚型
- IgG
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anti-TAG-72 / CA72.4 antibody
适用: 人, 犬, Cow, 大鼠, Hamster FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal B72-3 unconjugated
anti-TAG-72 / CA72.4 antibody适用: 人, 犬, Cow, 大鼠, Hamster IHC, StM 宿主: 小鼠 Monoclonal rB72-3 unconjugated Recombinant Antibody
anti-TAG-72 / CA72.4 antibody适用: 人, 犬, Cow, 大鼠, Hamster IHC, StM 宿主: 兔 Monoclonal CA72-2869R unconjugated Recombinant Antibody
anti-TAG-72 / CA72.4 antibody适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CA72-145 unconjugated
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应用备注
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Positive Control: Jurkat cells, Breast or lung carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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缓冲液
- 10 mM PBS without BSA and without Azide.
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储存液
- Azide free
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
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有效期
- 24 months
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- TAG-72 / CA72.4
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别名
- TAG-72 / CA72.4 (Tumor-Associated Glycoprotein)
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分子量
- 220kDa
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基因ID
- 182875
抗原
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