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SULT1E1 抗体

This anti-SULT1E1 antibody is a 小鼠 单克隆 antibody detecting SULT1E1 in WB 和 IHC (f). Suitable for 人.
产品编号 ABIN6938465
发货至: 中国

Quick Overview for SULT1E1 抗体 (ABIN6938465)

抗原

See all SULT1E1 抗体
SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SULT1E1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

CPTC-SULT1E1-1
  • 特异性

    The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human SULT1E1 protein

    亚型

    IgG2b kappa
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Liver tissue lysates. Human liver, intestine or kidney.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

    别名

    SULT1E1

    背景

    EST, EST-1,EST1, Estrogen sulfotransferase, estrogen-preferring, estrone sulfotransferase, ST1E1, STE, Sulfotransferase 1E1, Sulfotransferase , Sulfotransferase estrogen preferring,Sulfotransferase family 1E, estrogen-preferring, member 1
    Cellular localisation: Cytoplasm

    分子量

    35kDa

    基因ID

    6783, 479898

    UniProt

    P49888

    途径

    Steroid Hormone Biosynthesis
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