SPTAN1 抗体 (AA 2351-2475)
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- 抗原 See all SPTAN1 抗体
- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
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抗原表位
- AA 2351-2475
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SPTAN1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous and chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin I and spectrin I are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin II (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin II, a neuronal cytoskeleton protein.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment of human SPTAN1 protein (around aa 2351-2475) (exact sequence is proprietary)
- 克隆位点
- SPTAN1-3351
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product SPTAN1 Primary Antibody
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anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 950-1130) antibody
SPTAN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2071-2269) antibodySPTAN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 1573-1742) antibodySPTAN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) antibodySPTAN1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2351-2475) antibodySPTAN1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SPTAN1-3351 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 289-408) antibodySPTAN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 977-991) antibodySPTAN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50708 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 2351-2475) antibodySPTAN1 适用: 人 IHC, ELISA, Coat 宿主: 小鼠 Monoclonal SPTAN1-3352 unconjugated
anti-Spectrin alpha Chain, Brain (SPTAN1) (AA 1004-1181) antibodySPTAN1 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human colon or kidney tissues (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
- 别名
- SPTAN1 (SPTAN1 产品)
- 别名
- im:7157190 antibody, wu:fa20e05 antibody, wu:fb33g08 antibody, wu:fk32a10 antibody, zgc:112229 antibody, 2610027H02Rik antibody, Spna-2 antibody, Spna2 antibody, EIEE5 antibody, NEAS antibody, SPTA2 antibody, A2a antibody, IPF antibody, SPECA antibody, spectrin alpha, non-erythrocytic 1 antibody, spectrin, alpha, non-erythrocytic 1 antibody, SPTAN1 antibody, sptan1 antibody, Sptan1 antibody
- 背景
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Alpha-II spectrin, brain, EIEE5, Fodrin alpha chain, NEAS, Non erythrocytic spectrin alpha, non-erythroid alpha chain, SPECA, Spectrin alpha chain brain, Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spna2, SPTA2,Fodrin / Alpha Spectrin II (SPTAN1) / NEAS
Cellular localisation: Cytoplasm - 分子量
- 240kDa
- 基因ID
- 6709, 372331
- UniProt
- Q13813
- 途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
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