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SELPLG 抗体

SELPLG 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal PSGL1-1601 unconjugated
产品编号 ABIN6938364
发货至: 中国
  • 抗原 See all SELPLG 抗体
    SELPLG (Selectin P Ligand (SELPLG))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This SELPLG antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human SELPLG (CD162) protein
    克隆位点
    PSGL1-1601
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SELPLG Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat cells. Tonsil or Spleen.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    SELPLG (Selectin P Ligand (SELPLG))
    别名
    SELPLG (SELPLG 产品)
    别名
    CD162 antibody, CLA antibody, PSGL-1 antibody, PSGL1 antibody, SELPLG antibody, SELPG antibody, Psgl-1 antibody, Psgl1 antibody, Selp1 antibody, Selpl antibody, selectin P ligand antibody, selectin, platelet (p-selectin) ligand antibody, clasper antibody, SELPLG antibody, Selplg antibody, cla antibody
    背景
    CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG,CD162 (Selectin P Ligand)
    Cellular localisation: Cell Surface
    分子量
    43-120kDa
    基因ID
    6404, 591014
    UniProt
    Q14242
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