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s100a4 抗体

S100A4 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal CPTC-S100A4-3 unconjugated
产品编号 ABIN6938337
发货至: 中国
  • 抗原 See all s100a4 (S100A4) 抗体
    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
    适用
    • 86
    • 60
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    宿主
    • 73
    • 26
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    小鼠
    克隆类型
    • 63
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    单克隆
    标记
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    This s100a4 antibody is un-conjugated
    应用范围
    • 86
    • 47
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100A4 has been implicated in the progression and prognosis of several forms of human cancer, e.g. breast, colorectal, gastric, pancreatic and bladder cancer, SCLC and oesophageal squamous cell carcinoma, among others. Poor prognosis associated with high S100A4 expression is accompanied by clear signs of disease progression, e.g. high histological and clinical grades and involvement of lymph nodes.Also indicative of poor prognosis is high S100A4 expression coupled with reduced E-cadherin expression in pancreatic, oral squamous cell carcinoma and in melanoma. S100A4 expression is inversely related with expression of metastasis suppressor nm23 and with prognosis of breast cancer. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human S100A4 full length protein
    克隆位点
    CPTC-S100A4-3
    亚型
    IgG2c kappa
    Top Product
    Discover our top product S100A4 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: T98G, HeLa, A549 or A375 cells. Placenta, small intestine.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
    别名
    S100A4 (S100A4 产品)
    别名
    18A2 antibody, 42A antibody, CAPL antibody, FSP1 antibody, MTS1 antibody, P9KA antibody, PEL98 antibody, 42a antibody, Capl antibody, FSp1 antibody, Mts1 antibody, PeL98 antibody, metastasin antibody, pk9a antibody, S100A4 antibody, P9ka antibody, RNP9KA antibody, S100 calcium binding protein A4 antibody, S100 calcium-binding protein A4 antibody, S100A4 antibody, S100a4 antibody
    背景
    S100 calcium-binding protein A4, Calvasculin, CAPL, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignant transformation suppression 1 (MTS1), Metastasin, Placental calcium-binding protein,S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis)
    Cellular localisation: Nucleus and cytoplasm.
    分子量
    12kDa
    基因ID
    6275, 654444
    UniProt
    P26447
    途径
    S100 Proteins
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