S100A2 抗体
Quick Overview for S100A2 抗体 (ABIN6938332)
抗原
See all S100A2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer.
-
交叉反应 (详细)
- Human.
-
纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
免疫原
- Recombinant full-length human S100A2 protein
-
亚型
- IgG2b kappa
-
-
-
-
应用备注
-
Known_Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa. A549, HACAT, BxPC3 and A431 cell lysates, Skin and squamous cell cervical carcinoma.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
有效期
- 24 months
-
-
- S100A2 (S100 Calcium Binding Protein A2 (S100A2))
-
别名
- S100A2
-
背景
-
CAN19, MGC111539, S100L,S100A2 / S100 Calcium Binding Protein A2
Cellular localisation: Nucleus and cytoplasm. -
分子量
- 11.12kDa
-
基因ID
- 6273, 516484
-
UniProt
- P29034
-
途径
- S100 Proteins
抗原
-