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RBP4 抗体

The 小鼠 单克隆 anti-RBP4 antibody is suitable to detect RBP4 in samples from 人, 小鼠, 大鼠, 兔, 猴 和 山羊. It has been validated for WB, IHC 和 IF.
产品编号 ABIN6938313
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RBP4 抗体 (ABIN6938313)

抗原

See all RBP4 抗体
RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

适用

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人, 小鼠, 大鼠, 兔, 猴, 山羊

宿主

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小鼠

克隆类型

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单克隆

标记

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This RBP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

SPM442
  • 原理

    Retinol Binding Protein (RBP) Antibody

    特异性

    Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This MAb recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

    交叉反应 (详细)

    Human. Monkey. Goat. Rabbit. Rat. Mouse.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Retinol binding protein Purified from human plasma

    亚型

    IgG1, kappa
  • 应用备注

    Known_Application: Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Liver or placenta.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

    别名

    RBP

    背景

    Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma

    Liver or placenta.

    分子量

    21-25kDa

    基因ID

    5947, 529571

    UniProt

    P09455

    途径

    Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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