Recombinant PTH 抗体 (AA 1-34)
Quick Overview for Recombinant PTH 抗体 (AA 1-34) (ABIN6938264)
抗原
See all PTH 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-34
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特异性
- Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
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交叉反应 （详细）
- Human. Predicted to react with Mouse. Rat. Rabbit. Cow. Dog. Pig. Deer. Orangutan.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide (exact sequence is proprietary)
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亚型
- IgG
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anti-Parathyroid Hormone (PTH) antibody
PTH 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-2295R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-525R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parathyroid Hormone (PTH) (AA 32-115) antibodyPTH 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Parathyroid Hormone (PTH) antibodyPTH 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal 105G7 unconjugated
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 兔 Monoclonal PTH-1717R unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 1-34) antibodyPTH 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rPTH-911 unconjugated Recombinant Antibody
anti-Parathyroid Hormone (PTH) (AA 71-115) antibodyPTH 适用: 人 IHC, ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human parathyroid gland carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PTH (Parathyroid Hormone (PTH))
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别名
- PTH
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物质类
- Hormone
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背景
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HPTH, Parathormone, Parathyrin, Parathyroid hormone 1 (PTH1), Parathyroid hormone (PTH),Parathyroid Hormone (PTH) (N-Terminal)
Cellular localisation: Cytoplasmic and Secreted -
分子量
- 9kDa
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基因ID
- 5741, 37045
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UniProt
- P01270
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途径
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
-
