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Plasma Cell Marker 抗体

This anti-Plasma Cell Marker antibody is a 小鼠 单克隆 antibody detecting Plasma Cell Marker in IHC 和 StM. Suitable for 人.
产品编号 ABIN6938189
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Plasma Cell Marker 抗体 (ABIN6938189)

抗原

Plasma Cell Marker

适用

宿主

  • 9
小鼠

克隆类型

  • 9
单克隆

标记

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 7
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

LIV3G11-same as 7B18
  • 特异性

    It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm, their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.

    无交叉反应

    大鼠

    纯化方法

    Purified by Protein A/G

    免疫原

    Pancreatic cancer-related mucin

    亚型

    IgG2a kappa
  • 应用备注

    Positive Control: Tonsil or lymph node.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 minutes at RT) [(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 缓冲液

    10 mM PBS without BSA and without Azide.

    储存液

    Azide free

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

    有效期

    24 months
  • 抗原

    Plasma Cell Marker
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