Plakophilin 1 抗体 (N-Term)
Quick Overview for Plakophilin 1 抗体 (N-Term) (ABIN6938188)
抗原
See all Plakophilin 1 (PKP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- Recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.
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交叉反应 （详细）
- Human. Mouse.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- N-terminus of human Plakophilin-1 protein
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亚型
- IgG1 kappa
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anti-Plakophilin 1 (PKP1) (AA 235-726) antibody
PKP1 适用: 人, 小鼠 WB, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 19F10 unconjugated
anti-Plakophilin 1 (PKP1) (N-Term) antibodyPKP1 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 10B2 unconjugated
anti-Plakophilin 1 (PKP1) (AA 500-742) antibodyPKP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plakophilin 1 (PKP1) (AA 1-726) antibodyPKP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: U87, HeLa and A431 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Plakophilin 1 (PKP1)
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别名
- PKP1
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背景
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B6P, Band 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome),Plakophilin-1 (PKP1)
Cellular localisation: Cell Surface and nuclear -
分子量
- 75kDa
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基因ID
- 5317, 497350
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UniProt
- Q13835
抗原
-
