PDCD1LG2 抗体 (AA 27-220)
Quick Overview for PDCD1LG2 抗体 (AA 27-220) (ABIN6938141)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 27-220
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特异性
- Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-118) antibody
PDCD1LG2 适用: 人 WB, FACS, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 7F11D11 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 27-220) antibodyPDCD1LG2 适用: 人 WB, FACS, ELISA, IF, Coat 宿主: 小鼠 Monoclonal PDL2-2676 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 36-219) antibodyPDCD1LG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibodyPDCD1LG2 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal 24F-10C12 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) antibody (PE)PDCD1LG2 适用: 人 FACS 宿主: 小鼠 Monoclonal 24F-10C12 PE
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 21-268) antibodyPDCD1LG2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 22-111) antibodyPDCD1LG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D5 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 33-236) antibodyPDCD1LG2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 40-75), (N-Term) antibodyPDCD1LG2 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 2011CT786-31-38 unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL),Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: Jurakt, HepG2, THP-1, RAW, NIH3T3, U87 cells Placenta or Pancreas. Thyroid Carcinoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- PDCD1LG2
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背景
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B7 dendritic cell molecule, B7-DC, B7DC, Btdc, Butyrophilin B7DC, CD273, PD-L2, PDCD1L2, PDCD1LG2, PDL2, Programmed death ligand 2,PD-L2 / PDCD1LG2 / CD273
Cellular localisation: Cytoplasmic and Cell Surface -
分子量
- 31kDa
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基因ID
- 80380, 532279, 617872
抗原
-
