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PDCD1LG2 抗体 (AA 27-220)

PDCD1LG2 适用: 人 FACS 宿主: 小鼠 Monoclonal PDL2-1850 unconjugated
产品编号 ABIN6938140
发货至: 中国
  • 抗原 See all PDCD1LG2 抗体
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    抗原表位
    • 9
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    • 2
    • 2
    • 2
    • 1
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    AA 27-220
    适用
    • 68
    • 23
    • 10
    • 3
    宿主
    • 47
    • 24
    • 10
    • 1
    小鼠
    克隆类型
    • 45
    • 34
    • 1
    单克隆
    标记
    • 47
    • 9
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDCD1LG2 antibody is un-conjugated
    应用范围
    • 48
    • 38
    • 35
    • 30
    • 15
    • 11
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    Flow Cytometry (FACS)
    特异性
    Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
    克隆位点
    PDL2-1850
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PDCD1LG2 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.

    Positive_Control: Placenta or Pancreas. Thyroid Carcinoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    别名
    PDCD1LG2 (PDCD1LG2 产品)
    别名
    PDL2 antibody, B7DC antibody, Btdc antibody, CD273 antibody, PD-L2 antibody, PDCD1L2 antibody, bA574F11.2 antibody, B7-DC antibody, F730015O22Rik antibody, programmed cell death 1 ligand 2 antibody, PDCD1LG2 antibody, Pdcd1lg2 antibody
    背景
    B7 dendritic cell molecule, B7-DC, B7DC, Btdc, Butyrophilin B7DC, CD273, PD-L2, PDCD1L2, PDCD1LG2, PDL2, Programmed death ligand 2,PD-L2 / PDCD1LG2 / CD273
    Cellular localisation: Cytoplasmic and Cell Surface
    分子量
    31kDa
    基因ID
    80380, 532279, 617872
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