PAX7 抗体 (AA 301-505)
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北京 101111
Quick Overview for PAX7 抗体 (AA 301-505) (ABIN6938124)
抗原
See all PAX7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 301-505
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原理
- PAX7 (Rhabdomyosarcoma Marker) Antibody
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特异性
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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交叉反应 (详细)
- Human. Mouse. Rat Chicken. Zebrafish.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
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Known_Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, Jurkat, A431, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PAX7 (Paired Box 7 (PAX7))
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别名
- PAX7
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背景
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HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2
A431, HeLa, Jurkat, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS).
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分子量
- 57kDa
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基因ID
- 5081, 113253
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UniProt
- P23759
抗原
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