NFE2L1 抗体
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- 抗原 See all NFE2L1 抗体
- NFE2L1 (Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NFE2L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The NF-E2 DNA binding protein is composed of two subunits, p45 and MafK, and it regulates expression of globin genes in developing erythroid cells through interaction with Maf recognition elements (MAREs). A family of NF-E2 related proteins, which are collectively known as the Cap 'n' collar (CNC) family and include Nrf1 (also designated TCF11), Nrf2 and Nrf3, are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE sequences. The Nrf proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. They do so by heterodimerizing with Jun family members (c-Jun, JunB and JunD) to activate gene expression, specifically the detoxifying enzyme, NQO1. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1. Nrf3 is highly expressed in placenta, B cells and monocytes.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human NRF1 protein
- 克隆位点
- NRF1-2609
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product NFE2L1 Primary Antibody
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anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) antibody
NFE2L1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (AA 515-772) antibodyNFE2L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) antibodyNFE2L1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal NRF1-2609 unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (AA 251-550) antibodyNFE2L1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) antibodyNFE2L1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (AA 677-771) antibodyNFE2L1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (N-Term) antibodyNFE2L1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (C-Term) antibodyNFE2L1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 猴, Hamster, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (AA 575-624) antibodyNFE2L1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (C-Term) antibodyNFE2L1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Ubiquitous expression, strongest in skeletal muscle.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- NFE2L1 (Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1))
- 别名
- NFE2L1 (NFE2L1 产品)
- 别名
- LCR-F1 antibody, NRF1 antibody, TCF11 antibody, AA408798 antibody, AW212678 antibody, Lcrf1 antibody, TCF-11 antibody, nfe2l1 antibody, nuclear factor, erythroid 2 like 1 antibody, nuclear factor, erythroid derived 2,-like 1 antibody, nuclear factor, erythroid 2-like 1 antibody, nuclear factor, erythroid 2 like 1 S homeolog antibody, nuclear factor, erythroid 2-like 1a antibody, NFE2L1 antibody, Nfe2l1 antibody, nfe2l1.S antibody, nfe2l1a antibody
- 背景
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Alpha pal, Alpha palindromic-binding protein, Alpha-pal, locus control region factor 1, NFE2 related factor 1, Nuclear respiratory factor 1 (NFR-1),NRF1
Cellular localisation: Nucleus. - 分子量
- 30kDa (bZIP region), 65-120kDa (glycosylated)
- 基因ID
- 4899, 654363
- UniProt
- Q16656
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