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MYCN 抗体

MYCN 适用: 人 WB, IF 宿主: 小鼠 Monoclonal NMYC-1 unconjugated
产品编号 ABIN6937987
发货至: 中国
  • 抗原 See all MYCN 抗体
    MYCN (N-Myc Proto-Oncogene Protein (MYCN))
    适用
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    宿主
    • 29
    • 6
    小鼠
    克隆类型
    • 31
    • 4
    单克隆
    标记
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    This MYCN antibody is un-conjugated
    应用范围
    • 23
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.
    交叉反应 (详细)
    Human. Mouse. Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human n-Myc protein.
    克隆位点
    NMYC-1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product MYCN Primary Antibody
  • 应用备注

    Known_Application: Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T whole cell lysates or recombinant Human n-Myc protein.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MYCN (N-Myc Proto-Oncogene Protein (MYCN))
    别名
    MYCN (MYCN 产品)
    别名
    MODED antibody, MYCNOT antibody, N-myc antibody, NMYC antibody, ODED antibody, bHLHe37 antibody, Nmyc antibody, Nmyc-1 antibody, Nmyc1 antibody, c-nmyc antibody, Nmuc1 antibody, fb57a02 antibody, nmyc1 antibody, wu:fb57a02 antibody, zgc:85706 antibody, XN-myc antibody, XNmyc antibody, mycn antibody, mycn-a antibody, mycn-b antibody, mycna antibody, xN-myc1 antibody, MYCN proto-oncogene, bHLH transcription factor antibody, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog antibody, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived antibody, olfactory receptor 8S1 antibody, MYCN proto-oncogene, bHLH transcription factor S homeolog antibody, MYCN antibody, Mycn antibody, LOC515887 antibody, mycn antibody, mycn.S antibody
    背景
    Class E basic helix-loop-helix protein 37 (bHLHe37), MODED, N-myc proto-oncogene protein, Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene, ODED, pp65/67, v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived,n-Myc (Neuroblastoma Marker)
    Cellular localisation: Nucleus.
    分子量
    67kDa
    基因ID
    4613, 25960
    UniProt
    P04198
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