MYCN 抗体
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北京 101111
Quick Overview for MYCN 抗体 (ABIN6937987)
抗原
See all MYCN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.
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交叉反应 （详细）
- Human. Mouse. Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human n-Myc protein.
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亚型
- IgG2a kappa
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anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 401-464) antibody
MYCN 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 168-267) antibodyMYCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 337-464) antibodyMYCN 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2A4E9 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-100) antibodyMYCN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) antibodyMYCN 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (Internal Region) antibodyMYCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) antibodyMYCN 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-464) antibodyMYCN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (AA 1-100) antibodyMYCN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-N-Myc Proto-Oncogene Protein (MYCN) (C-Term) antibodyMYCN 适用: 人 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: 293T whole cell lysates or recombinant Human n-Myc protein.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- MYCN (N-Myc Proto-Oncogene Protein (MYCN))
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别名
- MYCN
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背景
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Class E basic helix-loop-helix protein 37 (bHLHe37), MODED, N-myc proto-oncogene protein, Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene, ODED, pp65/67, v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived,n-Myc (Neuroblastoma Marker)
Cellular localisation: Nucleus. -
分子量
- 67kDa
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基因ID
- 4613, 25960
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UniProt
- P04198
抗原
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