MYB 抗体 (AA 119-135)
Quick Overview for MYB 抗体 (AA 119-135) (ABIN6937978)
抗原
See all MYB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-135
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特异性
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein, coupled to KLH
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亚型
- IgG1 kappa
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anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 281-294) antibody
Verified MYB 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 1-640) antibodyMYB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (pSer532) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 305-558) antibodyMYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (N-Term) antibodyMYB 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (AA 1-50) antibodyMYB 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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别名
- MYB
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背景
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C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog,c-Myb Oncoprotein
Cellular localisation: Nuclear -
分子量
- ~75kDa
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基因ID
- 4602, 606320
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UniProt
- P01104
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途径
- Chromatin Binding, Positive Regulation of Immune Effector Process
抗原
-
