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MYB 抗体 (AA 119-135)

This anti-MYB antibody is a 小鼠 单克隆 antibody detecting MYB in ELISA 和 Coat. Suitable for 人.
产品编号 ABIN6937978
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for MYB 抗体 (AA 119-135) (ABIN6937978)

抗原

See all MYB 抗体
MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

适用

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宿主

  • 106
  • 20
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小鼠

克隆类型

  • 97
  • 34
单克隆

标记

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This MYB antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)

克隆位点

MYB286
  • 抗原表位

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    AA 119-135

    特异性

    The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein, coupled to KLH

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

    别名

    MYB

    背景

    C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog,c-Myb Oncoprotein
    Cellular localisation: Nuclear

    分子量

    ~75kDa

    基因ID

    4602, 606320

    UniProt

    P01104

    途径

    Chromatin Binding, Positive Regulation of Immune Effector Process
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