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MUC6 抗体

MUC6 适用: 人 IHC, IHC (f) 宿主: 小鼠 Monoclonal MUC6-916 unconjugated
产品编号 ABIN6937970
发货至: 中国
  • 抗原 See all MUC6 抗体
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    适用
    • 49
    • 4
    • 1
    宿主
    • 28
    • 21
    小鼠
    克隆类型
    • 33
    • 16
    单克隆
    标记
    • 22
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    • 2
    • 2
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    • 1
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    This MUC6 antibody is un-conjugated
    应用范围
    • 22
    • 20
    • 19
    • 16
    • 15
    • 6
    • 6
    • 6
    • 4
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    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
    无交叉反应
    大鼠
    交叉反应 (详细)
    Human. Does not react with Rat.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary)
    克隆位点
    MUC6-916
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MUC6 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Human stomach tissue (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    别名
    MUC6 (MUC6 产品)
    别名
    gastric antibody, MUC-6 antibody, mucin-6-like antibody, mucin 6, oligomeric mucus/gel-forming antibody, mucin 6, gastric antibody, LOC100850574 antibody, MUC6 antibody, Muc6 antibody
    背景
    Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6,MUC6 (Mucin 6 / Gastric Mucin)
    Cellular localisation: Cytoplasmic & Secreted
    分子量
    252kDa
    基因ID
    4588, 528432
    UniProt
    Q6W4X9
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