MUC6 抗体
Quick Overview for MUC6 抗体 (ABIN6937970)
抗原
See all MUC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
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无交叉反应
- 大鼠
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交叉反应 （详细）
- Human. Does not react with Rat.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) (AA 2338-2439) antibody
MUC6 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, StM 宿主: 兔 Monoclonal MUC6-1553R unconjugated Recombinant Antibody
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-806R unconjugated Recombinant Antibody
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC6-916 unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal CLH5 unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) (AA 2338-2439) antibody (Biotin)MUC6 适用: 人 WB 宿主: 兔 Polyclonal Biotin
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) (C-Term) antibodyMUC6 适用: 人, 小鼠 IF, WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 6, Oligomeric Mucus/gel-Forming (MUC6) antibodyMUC6 适用: 人 IF, WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal MUC6-916 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Human stomach tissue (IHC).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
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别名
- MUC6
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背景
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Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6,MUC6 (Mucin 6 / Gastric Mucin)
Cellular localisation: Cytoplasmic & Secreted -
分子量
- 252kDa
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基因ID
- 4588, 528432
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UniProt
- Q6W4X9
抗原
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