MTAP 抗体 (AA 97-196)
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- 抗原 See all MTAP 抗体
- MTAP (Methylthioadenosine phosphorylase (MTAP))
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抗原表位
- AA 97-196
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MTAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
- 克隆位点
- MTAP-1813
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product MTAP Primary Antibody
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anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-154) antibody
MTAP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) antibodyMTAP 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 WB, ELISA, IHC, Coat, StM 宿主: 兔 Monoclonal MTAP-3137R unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal MTAP-1813 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal rMTAP-1813 unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) (Internal Region) antibodyMTAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 8-37), (N-Term) antibodyMTAP 适用: 人 WB 宿主: 兔 Polyclonal RB42759 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
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- 应用备注
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, A431, HeLa, HAP1 or MCF-7 cells. Kidney.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- MTAP (Methylthioadenosine phosphorylase (MTAP))
- 别名
- MTAP (MTAP 产品)
- 别名
- BDMF antibody, DMSFH antibody, DMSMFH antibody, LGMBF antibody, MSAP antibody, c86fus antibody, Cc1-6 antibody, 1300019I21Rik antibody, MTAPase antibody, zgc:66012 antibody, mtap antibody, methylthioadenosine phosphorylase antibody, 5'-methylthioadenosine phosphorylase antibody, 6-oxopurine nucleoside phosphorylase antibody, methylthioadenosine phosphorylase L homeolog antibody, MTAP antibody, Mtap antibody, mtaP antibody, MMAH_RS04260 antibody, TAGG_RS05050 antibody, Toce_0364 antibody, VDIS_RS03165 antibody, MFER_RS02485 antibody, Intca_0886 antibody, DESMU_RS05370 antibody, Dester_1490 antibody, ARCVE_RS05445 antibody, Mahau_1873 antibody, MZHIL_RS01440 antibody, mtap antibody, mtap.L antibody
- 背景
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BDMF, DMSFH, DMSMFH, Epididymis luminal protein 249, HEL249, LGMBF, MeSAdo phosphorylase, Methylthioadenosine phosphorylase, MSAP, MTA phosphorylase, MTAP, MTAPase, S-methyl-5''-thioadenosine phosphorylase,MTAP (Tumor Suppressor Marker)
Cellular localisation: Cytoplasmic - 分子量
- 31kDa
- 基因ID
- 4507, 193268
- UniProt
- Q13126
- 途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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