LMO2 抗体 (AA 23-140)
Quick Overview for LMO2 抗体 (AA 23-140) (ABIN6937789)
抗原
See all LMO2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 23-140
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特异性
- The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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别名
- LMO2
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背景
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Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2,LMO2 (B-Cell Marker)
Cellular localisation: Nuclear -
分子量
- 24kDa
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基因ID
- 4005, 34560
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UniProt
- P25791
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途径
- Chromatin Binding
抗原
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