L1CAM 抗体
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北京 101111
Quick Overview for L1CAM 抗体 (ABIN6937764)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD171 / NCAM-L1 (Axonal Marker) Antibody
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特异性
- Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Homogenous suspension of 16-week human fetal brain
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亚型
- IgG1, kappa
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anti-L1 Cell Adhesion Molecule (L1CAM) (AA 1143-1257) antibody
L1CAM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 犬, 猴 WB, FACS, IF 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人, 猴 WB, FACS 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 20-197) antibodyL1CAM 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5C6A10 unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyL1CAM 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 653-667), (Extracellular) antibodyL1CAM 适用: 人 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 526-690) antibodyL1CAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 995-1119) antibodyL1CAM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-L1 Cell Adhesion Molecule (L1CAM) (AA 550-900) antibodyL1CAM 适用: 人 IHC 宿主: 小鼠 Monoclonal 171R unconjugated Recombinant Antibody
anti-L1 Cell Adhesion Molecule (L1CAM) antibodyKD Validated L1CAM 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB3690 unconjugated
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Neuroblastomas or Schwannomas.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- L1CAM
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背景
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CAML1, HSAS1, Hyd, L1 Cell Adhesion Molecule, L1-NCAM, MASA, MIC5, NCAM-L1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, S10, SPG1
Neuroblastomas or Schwannomas.
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分子量
- 220-240kDa
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基因ID
- 3897, 52818
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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