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KRT6A 抗体

KRT6A 适用: 人 FACS, IHC (f) 宿主: 小鼠 Monoclonal KRT6A-2368 unconjugated
产品编号 ABIN6937715
发货至: 中国
  • 抗原 See all KRT6A 抗体
    KRT6A (Keratin 6A (KRT6A))
    适用
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    宿主
    • 61
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    小鼠
    克隆类型
    • 59
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    单克隆
    标记
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    This KRT6A antibody is un-conjugated
    应用范围
    • 57
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    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas..
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human Cytokeratin 6A (KRT6A) protein
    克隆位点
    KRT6A-2368
    亚型
    IgG2a kappa
    Top Product
    Discover our top product KRT6A Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells, Tonsil or Basal Cell Carcinoma (BCC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    KRT6A (Keratin 6A (KRT6A))
    别名
    KRT6A (KRT6A 产品)
    别名
    CK6A antibody, CK6C antibody, CK6D antibody, K6A antibody, K6C antibody, K6D antibody, KRT6C antibody, KRT6D antibody, 2310016L08Rik antibody, Krt2-6a antibody, Krt2-6c antibody, MK6a antibody, mK6[a] antibody, CK-6A antibody, Krt6a antibody, KRT6A antibody, keratin 6A antibody, similar to keratin complex 2, basic, gene 6a antibody, keratin, type II cytoskeletal 6A antibody, KRT6A antibody, Krt6a antibody, LOC683313 antibody, LOC101112304 antibody
    背景
    58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5,Cytokeratin 6A (KRT6A) (Basal Cell Marker)
    Cellular localisation: Cytoplasmic
    分子量
    56kDa
    基因ID
    3853, 700779
    UniProt
    P02538
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