KRT6A 抗体
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北京 101111
Quick Overview for KRT6A 抗体 (ABIN6937715)
抗原
See all KRT6A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas..
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human Cytokeratin 6A (KRT6A) protein
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亚型
- IgG2a kappa
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anti-Keratin 6A (KRT6A) (AA 163-468) antibody
KRT6A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal KRT6A-2368 unconjugated
anti-Keratin 6A (KRT6A) (AA 253-352) antibodyKRT6A 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7E3D1 unconjugated
anti-Keratin 6A (KRT6A) (AA 2-564) antibodyKRT6A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) (AA 163-468) antibodyKRT6A 适用: 人 WB 宿主: 小鼠 Monoclonal D9 unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) (AA 305-564) antibodyKRT6A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Keratin 6A (KRT6A) antibodyKRT6A 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB14175 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells, Tonsil or Basal Cell Carcinoma (BCC).
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- KRT6A (Keratin 6A (KRT6A))
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别名
- KRT6A
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背景
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58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5,Cytokeratin 6A (KRT6A) (Basal Cell Marker)
Cellular localisation: Cytoplasmic -
分子量
- 56kDa
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基因ID
- 3853, 700779
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UniProt
- P02538
抗原
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