Cytokeratin 19 抗体
Quick Overview for Cytokeratin 19 抗体 (ABIN6937692)
抗原
See all Cytokeratin 19 (KRT19) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40 kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50 % -60 % of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
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无交叉反应
- 雪貂, 大鼠
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交叉反应 （详细）
- Human. Does not react with Rat or Ferret.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Human breast cancer MCF-7 cells
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亚型
- IgG2a kappa
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anti-Keratin 19 (KRT19) antibody
KRT19 适用: 人 WB, ELISA, IHC (p), ICC, IP, ICFC 宿主: 小鼠 Monoclonal A53-B-A2 unconjugated
anti-Keratin 19 (KRT19) (AA 245-391) antibodyKRT19 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 19 (KRT19) (AA 245-391) antibodyKRT19 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal D1 unconjugated
anti-Keratin 19 (KRT19) (AA 1-403) antibodyKRT19 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 19 (KRT19) (AA 127-322) antibodyKRT19 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Keratin 19 (KRT19) antibodyKRT19 适用: 人, 小鼠, 大鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal KRT19-800 unconjugated
anti-Keratin 19 (KRT19) antibodyKRT19 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal KRT19-799 unconjugated
anti-Keratin 19 (KRT19) antibodyKRT19 适用: 人 WB, IHC (p), ICC, IP, ICFC 宿主: 小鼠 Monoclonal BA-17 unconjugated
anti-Keratin 19 (KRT19) (AA 241-400) antibodyKRT19 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 19 (KRT19) (AA 274-400) antibodyKRT19 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 8H1A8 unconjugated
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应用备注
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Known_Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, HeLa or Hep-G2 cells, Breast cancer tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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别名
- KRT19
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背景
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K19, k1cs, Keratin 19 Keratin Type i 40kD, krt19,Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker)
Cellular localisation: Cytoplasmic -
分子量
- 40kDa
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基因ID
- 3880, 654568
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UniProt
- P08727
抗原
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