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KRT16 抗体 (C-Term)

This anti-KRT16 antibody is a 小鼠 单克隆 antibody detecting KRT16 in IHC (f). Suitable for 人.
产品编号 ABIN6937667
发货至: 中国

Quick Overview for KRT16 抗体 (C-Term) (ABIN6937667)

抗原

See all KRT16 抗体
KRT16 (Keratin 16 (KRT16))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This KRT16 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

LL025
  • 抗原表位

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    C-Term

    特异性

    Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    A synthetic peptide from the C-terminal of human Cytokeratin 16

    亚型

    IgG1 kappa
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells. Tonsil, Skin. Bladder or Cervix.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    KRT16 (Keratin 16 (KRT16))

    别名

    KRT16

    背景

    CK16, Cytokeratin-16, Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK), K1CP, Keratin Type I Cytoskeletal 16, Keratin-16, KRT16A,Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker)
    Cellular localisation: Cytoplasmic

    分子量

    48kDa

    基因ID

    3868, 655160

    UniProt

    P08779
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